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Colloidal drug delivery systems in antiinfective chemotherapy |
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| Abstract | A review and discussion. The potential application of colloidal drug delivery systems for antimicrobial, antiviral, antiprotozoal and antifungal chemotherapy is presented. In particular, the features of nanoparticles and liposomes are discussed. These colloidal carriers are capable of offering a suitable tool for increasing the selective delivery and the therapeutic effectiveness of a large no. of chemotherapeutic agents. After i.v. administration colloidal drug delivery systems are preferentially taken up by the RES. For this reason nanoparticles and liposomes may be used as antimicrobial drug carriers in the treatment of infections involving the RES. The delivery of antimicrobial drugs outside the RES can be achieved by adjusting the colloidal carrier size and coating the colloid surface with different non-ionic surfactants. | |
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| Altri Autori | Fresta Massimo | |
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19/Apr/16
Esito colloquio per conferimento Assegno di Ricerca CHIM 09 Esito colloquio A.R. ssd CHIM/09 |
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11/Apr/16
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24/Mar/16
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